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KMID : 1156220180440020196
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Journal of Environmental Health Sciences
2018 Volume.44 No. 2 p.196 ~ p.203
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Environmental Risk Assessment for Ivermectin, Praziquantel, Tamiflu and Triclosan
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Rye Tae-Kwon
Kim Jung-Kon
Kim Kyung-Tae
Lee Jae-Woo
Kim Ji-Eun
Cho Jae-Gu
Yoon Jun-Heon
Lee Jae-An
Kim Pil-Je
Ryu Ji-Sung
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Abstract
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Objectives: The purpose of this study was to assess environmental risk on the emerging contaminants of concern, such as ivermetin, parziquantel, tamiflu and triclosan. Furthermore, we tried to provide a more efficient management practice and a basis for future studies of risk assessment on those substances.
Methods: Predicted no effect concentration (PNEC) and predicted environmental concentration (PEC) were determined through modeling and literature reviews. Environmental risk assessment was evaluated by calculating HQ (hazard quotient) by a comparison of PEC (or measured environmental concentration (MEC)) and PNEC.
Results: HQ value of tamiflu calculated from MEC was 1.9E-03. For ivermectin and triclosan, the HQ values were not available because these were not detected in the aquatic environment. The toxicity of ivermectin and triclosan showed a very low value, indicating a high level of HQ. However, praziquantel can be categorized into the material that do not require management since they have less than HQ 1.
Conclusion: Based on the results of the initial risk assessment, it is assumed that the ivermectin and triclosan have potential to cause direct adverse effects on the aquatic environment. To conduct an accurate environmental risk assessment, the further study on PEC estimation of such contaminants should be actively carried out.
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KEYWORD
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Environmental risk assessment, contaminants of emerging concerns, pharmaceuticals, personal care products
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